Aug 16, 2020 · Polio vaccine, given multiple times, almost always protects a child for life. The development of effective vaccines to prevent paralytic polio was one of the major medical breakthroughs of the 20th century. There are six different vaccines to stop polio transmission: Inactivated polio vaccine (IPV) – protects against poliovirus types 1, 2, and 3

Dec 3, 2024 · Poliomyelitis (polio) is a highly infectious viral disease that largely affects children under 5 years of age. The virus is transmitted by person-to-person spread mainly through the faecal-oral route or, less frequently, by a common vehicle (e.g. contaminated water or food) and multiplies in the intestine, from where it can invade the nervous system and cause paralysis.

Oct 22, 2024 · Polio vaccine, given multiple times, can protect a child for life. There are two vaccines available: oral polio vaccine and inactivated polio vaccine . Both are effective and safe, and both are used in different combinations worldwide, depending on local epidemiological and programmatic circumstances, to ensure the best possible protection to ...

Oct 27, 2023 · Oral polio vaccine (OPV) contains an attenuated (weakened) vaccine-virus, activating an immune response in the body. When a child is immunized with OPV, the weakened vaccine-virus replicates in the intestine for a limited period, thereby developing immunity by building up antibodies. During this time, the vaccine-virus is also excreted.

Mar 1, 2024 · The first polio vaccine was developed by Jonas Salk, from formaldehyde-inactivated wild polio viruses. Salk’s IPV was tested and proved highly efficacious against paralytic poliomyelitis in a large clinical trial conducted in US schoolchildren in 1954, which was rapidly followed by licensure of the product and implementation of mass ...

On 11 July 2023, WHO received an official report regarding the detection of a circulating vaccine-derived poliovirus type 2 (cVDPV2) in two acute flaccid paralysis (AFP) cases and two asymptomatic healthy children community contacts from Hagadera refugee camp, in Kenya, the second largest refugee camp in the world with over 100 000 refugees. The genetic sequencing …

Jun 24, 2022 · In accordance with its mandate to provide guidance to Member States on health policy matters, WHO issues a series of regularly updated position papers on vaccines and combinations of vaccines against diseases that have an international public health impact. These papers are concerned primarily with the use of vaccines in large-scale immunization …

Apr 19, 2017 · Oral polio vaccine (OPV) contains an attenuated (weakened) vaccine-virus, activating an immune response in the body. When a child is immunized with OPV, the weakened vaccine-virus replicates in the intestine for a limited period, thereby developing immunity by building up antibodies. During this time, the vaccine-virus is also excreted.

Sep 13, 2024 · Around 560 000 children under ten years old were vaccinated against polio during the first round of an emergency vaccination campaign conducted in three phases from 1-12 September 2024 in the Gaza Strip. The 12-day campaign provided novel oral polio vaccine type 2 (nOPV2) to 558 963 children, following meticulous planning and coordination.

Jan 11, 2024 · Indonesia reported four cases of circulating vaccine-derived poliovirus type 2 (cVDPV2) from October 2022 to February 2023, with three cases occurring in Aceh province and one case in West Java province. On 20 and 27 December 2023, the Indonesian Ministry of Health notified WHO of two new confirmed cases of cVDPV2. One case, from Klaten District, Central …