Serum sickness is a rare but potentially severe complication of rituximab therapy. A patient with newly diagnosed progressive transformation of germinal centers (PTGC) associated with immunoglobulin ...

Researchers investigated the apparent close relationship between IGG4-RD and AAV and whether they arise from shared pathophysiological pathways. A 60-year-old woman was referred for fever and kidney ...

Emerging treatments, like gene and mRNA therapies, offer hope, pending further investigation. The ongoing development of new drugs for Fabry disease is expected to lead to a greater variety of ...

Genes such as NKG7 and ASCL2 were found to be key drivers of CLL and could inform drug sensitivity profiles. A distinct natural killer (NK) cell subset, termed CLL_NK, is a precursor to effector NK ...

Patients completing induction and prolonged MTR had a median overall survival of 143 months and a relapse-free survival of 122 months. A prolonged regimen of methotrexate, temozolomide, and rituximab ...

Patients with severe aplastic anemia showed significantly better long-term survival than those with lower risk hypoplastic MDS. A reduced megakaryocyte count may serve as a reliable distinguishing ...

AI’s capacity to analyze and classify large volumes of data can be leveraged to enhance both diagnosis and management in Fabry disease. Artificial intelligence (AI)-based tools could improve the ...

A poor response to ITP therapy, characterized by corticosteroid resistance or dependence, was also found to be associated with chronicity. Factors predicting chronicity in immune thrombocytopenia (ITP ...

Spontaneous recanalization following thrombotic occlusion without lipid-rich plaque is one of the representative etiologies of coronary artery disease in patients with myeloproliferative neoplasms ...

To improve outcomes, neonates with significant comorbidities such as sepsis and perinatal asphyxia on a background of FNAIT should be closely monitored. The prevalence of fetal and neonatal alloimmune ...

Remote epilepsy was strongly linked to poorer neurological outcomes, but timing of diagnosis did not affect long-term prognosis. Perinatal intracranial hemorrhage (pICH), including cases secondary to ...

In the case of Fabry disease, renal lysosomal inclusions were used as a surrogate biomarker that contributed to the approval of agalsidase beta. The role of biomarkers in diagnosis, severity ...