Your organisation needs to be registered as a stakeholder before we can accept comments. Not eligible? Contact the stakeholder organisation that most closely represents your interests and pass your ...

A caesarean during the second stage of labour is associated with an increased risk of adverse perinatal outcomes compared with an elective caesarean or a caesarean during the first stage of labour.

you can comment on draft recommendations the final recommendations are published published guidance is being reviewed. We'll use the information you provide on this form to contact you about the ...

There is a simple discount patient access scheme for leniolisib. NHS organisations can get details on the Commercial Access and Pricing (CAP) Portal. Non-NHS organisations can contact ...

Coding and clinical classification codes for this guidance. This guidance replaces NICE interventional procedures guidance on balloon disimpaction of the baby’s head at emergency caesarean during the ...

Leniolisib (Joenja, Pharming) is indicated for 'the treatment of activated phosphoinositide 3‑kinase delta (PI3Kδ) syndrome (APDS) in adult and paediatric patients 12 years of age and older'. The ...

Leniolisib is recommended, within its marketing authorisation, for treating activated phosphoinositide 3‑kinase delta syndrome (APDS) in people 12 years and over. Leniolisib is recommended only if the ...

The highly specialised technologies evaluation committee is a standing advisory committee of NICE. Committee members are asked to declare any interests in the technology being evaluated. If it is ...

Leniolisib (Joenja) is available on the NHS as a possible treatment for activated phosphoinositide 3-kinase delta syndrome in people 12 years and over. Is this treatment right for me? Your healthcare ...

Tools to help you put the guidance into practice.