Senate Democrats’ move Thursday to reject an industry-backed crypto bill delivered a significant blow to the digital asset lobby’s standing on Capitol Hill, where its agenda suddenly appears to be on wobbly ground.

A key procedural vote Thursday on a first-of-its-kind crypto regulation bill fell short in the Senate, facing opposition from Democrats amid ties between the crypto industry and the Trump family have threatened to tank the vote.

The move is a setback for the influential cryptocurrency industry, which spent heavily on congressional races last year.