Researchers at MIT have uncovered a powerful way the brain "unlearns" fear: through a dopamine-driven reward signal. By ...

A new study shows how a dopamine circuit between two brain regions enables mice to extinguish fear after a peril has passed.

Bringing mice to an enclosure and zapping their feet with tiny electric shocks, then bringing the mice back to the enclosure ...

The VTA was the lab’s prime suspect to be the source of the signal because the region is well known for encoding surprising experiences and instructing the brain, with dopamine, to learn from them.

Exploring how sex differences regulate dopamine responses could inform novel interventions to prevent or treat substance use ...