Neuroscientists at the Sainsbury Wellcome Center (SWC) at UCL have discovered that the brain uses a dual system for learning ...

Reconstructing the nigrostriatal pathway is one of the major challenges in cell replacement therapies for Parkinson's disease due to the lack of enabling technologies capable of guiding the ...

Neuroscientists at the Sainsbury Wellcome Centre (SWC) at UCL have discovered that the brain uses a dual system for learning through trial and error.

(6) The central pathological regions in PD are the substantia nigra and striatum. Please replace the staining results from the cortex and hippocampus with those from these regions in the PD model. The ...

it produces a selective N-type calcium channel blockage in the striatum in animal models. [50] It causes a significant decrease in single-unit neuronal firing in the substantia nigra pars reticulate.