Neuroscientists at the Sainsbury Wellcome Center (SWC) at UCL have discovered that the brain uses a dual system for learning ...

Reconstructing the nigrostriatal pathway is one of the major challenges in cell replacement therapies for Parkinson's disease due to the lack of enabling technologies capable of guiding the ...

They found there was inflammation and brain damage in the striatum following the stroke, which they had expected. What the researchers didn’t expect was the impact on another area of the brain, the ...

Altogether, the data indicate that lamotrigine limits dopaminergic neuronal death in the substantia nigra and promotes ... cells were counted in the striatum and the results were expressed as ...

Parkinson’s disease disrupts lives by slowly robbing people of their ability to move, speak, and function with ease. It's the ...

Parkinson's disease is characterized by the degeneration of dopamine-producing neurons in the substantia nigra pars compacta ... to dopamine depletion in the striatum and motor symptoms like ...

These toxic bundles gather in a region of the brain called the substantia nigra, where they damage and kill dopamine-producing neurons. Without enough dopamine, the brain struggles to control ...