"By imaging the whole transcriptome at the individual transcript level and advancing sensitivity across any in situ RNA assay, these developments in CosMx represent a historic milestone in the study ...

Multi-modal data integration of single-nuclei RNA and ATAC sequencing with spatial transcriptomics, provides new molecular insights into gene regulatory networks driving cell state transitions in ...

Researchers in Nikolaus Rajewsky's lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor's cellular neighborhoods in 3D and identify potential targets ...

CosMx SMI is spatial multiomics single-cell imaging solution. It enables rapid quantification and visualization of up to 1,000 RNA and 100 validated protein analytes at single-cell and subcellular ...

Methods: We performed following assays including 1) High-plex multiple IHC platform: PhenoCycler Fusion (PCF) protein-level spatial analysis (n=10), 2) FFPE Single-Cell RNA Sequencing (FFPE scRNA-seq) ...

Single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) have opened up new avenues that will expand our knowledge on cellular heterogeneity and spatial tissue architecture in the tumor ...

single cell RNA sequencing with 10XGenomics (10Xchromium controller and X) platform, Spatial transcriptomic sequencing with 10X Visium (including Visium HD), Spatial Molecular Imaging Nanostring CosMX ...

Akoya Biosciences (AKYA) and Enable Medicine announced a collaboration to deliver the largest commercially available single-cell spatial ...

BioSkryb Genomics and Tecan Group, today introduced a high-throughput single-cell workflow, combining BioSkryb's 384-well format of the ResolveOME™ Whole Genome and Transcriptome Single-Cell Core Kit ...

Extending this discovery recently in Cell, Flynn and colleagues showed that glycoRNAs form highly organized clusters with RNA-binding proteins on the cell surface. These clusters appear to ...