Oddsmakers project the San Francisco 49ers (6-10) to put up a fight in their attempt to break their three-game losing streak, ...

Never before in NFL history have two teams with at least 14 wins each gotten together for a regular-season matchup. But that ...

Conner initially suffered a right knee injury on a tackle in the third quarter of the Cardinals’ Week 16 loss to the Panthers ...

The stage is set for the biggest regular season game in NFL history as the Detroit Lions take on the Minnesota Vikings on ...

NFL Network's Ian Rapoport reported Friday, citing sources, that quarterback Trey Lance is expected to see "significant" run ...

Week 18 signals the end of a frustrating season for the Dallas Cowboys. They're eliminated from playoff contention, and have ...

Arizona State RB Cam Skattebo adds fuel to discussions linking him to San Francisco 49ers draft strategy amid backfield challenges.

The Seahawks hit the road for the final time this season as they get set to take on the division rival L.A. Rams in Week 18. Seahawks reporter Jen Mueller breaks down the Seahawks' final game of the ...

This year, Detroit surged to a 12-1 record to start the season and has been one of the top teams in the NFL for months. Both Lions' losses -- a 20-16 setback against Tampa Bay and a 48-42 defeat at ...

Check out the latest injury report for the 49ers, including Deebo Samuel's status ahead of the Week 18 showdown against the Cardinals.

The NFC West was turned upside down this season, as the San Francisco 49ers have been eliminated from the playoffs just one season removed from a trip to the Su ...

The Miami Dolphins are on the road for the last game of the regular season against the New York Jets on Sunday.