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"We think the bacteria's ribosomes might be altering its structure just enough to prevent an antibiotic from binding effectively," says Anna Delgado-Tejedor, first author of the study and Ph.D ...
These differences are exploited by antibiotics, which are designed to inhibit the prokaryotic ribosomes of infectious bacteria without affecting eukaryotic ribosomes, thereby not interfering with ...
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Bacteria Alter Ribosomes to Resist Common AntibioticsBacteria modify their ribosomes when exposed to widely used antibiotics, according to research published today in Nature Communications. The subtle changes might be enough to alter the binding ...
Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal ...
none were previously known to target the bacterial ribosome—the protein-making machinery itself. Gerry Wright and his research team discovered lariocidin by examining soil samples from a ...
Clindamycin and related drugs kill bacteria by inhibiting the ability of bacterial ribosomes to synthesize proteins, but don’t affect ribosomes in eukaryotic cells, including those of humans. Yet both ...
What if we could fight climate change using bacteria that live on air? That's the vision behind a newly funded international research project led by ...
Williams and Research Scientist Anton Petrov compared three-dimensional structures of ribosomes from a variety of species of varying biological complexity, including humans, yeast, bacteria and ...
We focus on how temperature affects the cytoplasmic state in bacteria and what the consequences to cellular ... tracking to record the movement of individual molecules, such as ribosome, inside ...
Bacteria are amongst the simplest of organisms ... Cell contents Cytoplasm, cell organelles include mitochondria, ribosomes and chloroplasts in plants. Cytoplasm, ribosomes present; there ...
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