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If I’ve convinced you that self-similar networks manifest from the highest level of human organizations, down to the smallest ...
Lariocidin may be the first of its kind to block one of the most essential components in bacterial survival: the ribosome. “Our old drugs are becoming less and less effective as bacteria become more ...
That process led to the group discovering a lasso peptide that exhibited broad-spectrum antibiotic activity and was effective at killing both gram-positive and gram-negative pathogenic bacteria, along ...
Lariocidin is a lasso peptide, a string of amino acids in a lasso shape that attacks bacteria and keeps it from ... "Lariocidin binds to the molecular machine, the ribosome, that makes all the ...
Most of these antibiotics are produced outside the ribosome, the cellular structure ... modifications set the three-dimensional shape of these peptides, facilitating their interactions with ...
To tie up a ribosome, an antibiotic first needs to get ... which takes on a more intricate three-dimensional shape, looping its tail to resemble a pretzel. This even more stable structure might ...
To tie up a ribosome, an antibiotic first needs to get ... which takes on a more intricate three-dimensional shape, looping its tail to resemble a pretzel. This even more stable structure might ...
Yet how livestock shapes the landscape depends on how the animals are farmed. Intensive farming of large livestock breeds can increase soil erosion and flood risk, while low-density regenerative ...