to "barcode" ribosomal RNA (rRNA) inside living cells. By writing genetic information directly into the 16S rRNA—a molecule ...

In 2023, tuberculosis (TB) killed about 1.25 million people worldwide, more than any other infectious disease on Earth — even though it is curable. Months- or even years-long regimens of potent ...

Part of the problem is that, once a patient starts taking the medication, clinicians can’t tell when the bacteria has been ... the TB bacterium’s 16S ribosomal RNA (rRNA) as a sensitive ...

For instance, bacteria contain a single type of RNA ... RNA pol I transcribes ribosomal RNAs (rRNAs), RNA pol II transcribes RNAs that will become messenger RNAs (mRNAs) and also small regulatory ...

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal ...

In bacterial cells, cold shock proteins (CSPs ... between the nascent peptide and amino acid residues in the ribosomal RNA, leading to a rearrangement in RF2, shifting it to an inactive conformation.

This image highlights two alternatives for the ribosome to be recruited to an mRNA that is still being synthesized by RNA ... dominant in bacteria, RNAP (green) can interact with ribosomal protein ...

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal cellular functions. The ...