Recently, a new class of therapeutics that disable the neonatal Fc receptor (FcRn), which protects IgG from degradation, has emerged to treat IgG-mediated autoimmune disease. 4,5 Here, we review ...

One of the primary mechanisms of SCFA benefits was the direct activation of a group of G-protein-coupled receptors (GPCRs), termed free fatty acid receptors (FFARs), the FFAR2 (GPR43), and FFAR3 ...

receptor agonist, which was being investigated for chronic weight management. Pfizer’s dose-optimization studies of once-daily formulations of danuglipron (NCT06567327 and NCT06568731 ...

Both function by binding to protein receptors on cells. The four primary receptors — alpha-1, alpha-2, beta-1, and beta-2 — are located in different body areas. The impact of norepinephrine and ...

Gymnema is a trace mineral that plays a crucial role in maintaining healthy GLUT-4 receptors, which are essential for glucose uptake in the body. Studies suggest that Gymnema can help reduce sugar ...

The effector proteolytically targets a key receptor while its activity is counteracted by host-mediated phosphorylation, revealing a dynamic interplay that fine-tunes symbiotic interactions. The ...

College of Plant Protection, Nanjing Agricultural University/State & Local Joint Engineering Research Center of Green Pesticide-Invention and Application, Nanjing 210095 Jiangsu, China ...

Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045 , United States Department of Pharmacology, University of Colorado Anschutz ...