Nail’d it! Scratching an itchy rash can feel sooo good — that’s because the rubbing creates a mild pain sensation that ...

Food allergy, or the aggressive immune system reaction following the consumption of a certain food or food ingredient, ...

New research published in the journal Science uncovers how scratching aggravates inflammation and swelling in a mouse model ...

Researchers studied genetically modified mice that lack NP2 itch-sensing neurons, to investigate the connection between itch, ...

Briquilimab targets c-Kit to address mast cell diseases. Patients saw substantial reductions in tryptase as early as week 1. 100% of patients with a single 240 mg dose had complete response at week 8.

Chlorcyclizine shows promise in reducing protoporphyrin-IX accumulation and liver damage in erythropoietic protoporphyria, ...

Researchers identify a pathogenic subset of CD8+ memory T-cells that promote airway tissue inflammation and recurrent respiratory diseases.

Food allergies can be life-threatening due to the rapid and exaggerated immune response. While mucosal mast cells (MMCs) are ...