Cleft lip and cleft palate are among the most common birth defects, occurring in about one in 1,050 births in the United ...

EPR Laboratory, International Tomography Center SB RAS, 3 Institutskaya Street, Novosibirsk 630090, Russia ...

The study presents a valuable finding on the role of cholesterol-binding sites on GLP-1 receptors although the clinical ramifications are unclear and not eminent at this point. Based on the detailed ...

Cholesterol is critical for mitochondrial membrane structure and function ... showed that CM-Pcsk9 –/– mice (mice with cardiomyocyte-specific deletion of the gene encoding PCSK9 [proprotein convertase ...

Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, 635 Barnhill, Indianapolis, Indiana46202-3082, United States ...

Chromosomal translocations involving the human CBFB gene are ... a putative CBFβ binding site on the CBFα Runt domain 13. Here, we describe the high-resolution solution structure of the CBFβ ...

In addition, the conformations of the circular DNA must avoid overlapping with ribosomes identitied in cryo-electron tomograms. While Syn3A lacks the complex regulatory systems known to orchestrate ...

tRNA structure and modifications, tiRNA induction of stress granule formation, and tRF regulation of gene expression through the repression of translation can all impact a cell’s fate. This review ...

We identify genes connected to mitochondrial function and ribosome biogenesis as direct MYC/HCF-1 targets and demonstrate how modulation of the MYC–HCF-1 interaction influences cell growth, metabolite ...