Several space agencies are planning crewed, long-duration missions beyond low-Earth orbit, introducing various health risks and challenges to astronauts. In this Review, Durante and colleagues ...

Avacopan treatment for antineutrophil cytoplasmic antibody–associated vasculitis demonstrated lower rates of adverse events, serious adverse events, white blood cell (WBC) count reductions ...

Syfovre (pegcetacoplan) is a prescription injection used in adults to treat geographic atrophy due to a certain type of age-related macular degeneration (AMD). Syfovre comes as a solution that’s ...

Macular degeneration is very common and affects an estimated 19.8 million people in the United States. Approximately one in 10 Americans age 50 and older have an early form of the disease and as many ...

Macular degeneration usually refers to the age-related degenerative changes in the retina that can result in loss of central vision. It is caused by abnormal blood vessel growth (a condition ...

Up to 80% of people with uteruses will develop fibroids by the age of 50. Fibroid degeneration is the breakdown of a fibroid through cell death. This is caused by ischemia (a lack of adequate blood ...

The comprehensive review covers all aspects of large vessel vasculitis from epidemiology, pathogenesis, morbidity and mortality, clinical investigation, treatment and prospects for the future. The ...

However, some people with RA will develop skin rashes. These can occur due to hives, vasculitis, and many other causes. RA is a chronic autoimmune disease that can affect many other parts or ...

Aims To characterise the association between visual field (VF) defects and myopic macular degeneration (MMD) in highly myopic adults without glaucoma. Methods Participants (n=106; 181 eyes) with high ...

Frontotemporal lobar degeneration (FTLD) is a neurodegenerative disease affecting the frontal and temporal lobes that regulate higher cognitive brain functions such as personality, behavior ...

All patients had non-infectious retinal vasculitis and at least 1 year of follow-up. Results Although occlusive vasculitis was rare, retinal neovascularisation occurred much more commonly in the ...