By integrating CRISPR-Cas9 induced gene editing with single cell RNA-Seq, high-resolution lineage tracing through molecular barcoding ... in silico experiment simulating lineage history from a ...

In a new study published in Developmental Cell on April ... a neurogenic lineage tree, tracing how different types of hypothalamic neurons develop from various progenitor regions.

The expression of its genes was confirmed also in several types of human bone marrow-derived stem cells: mononuclear cells (MNCs), very small embryonic-like stem cells (VSELs), hematopoietic ...

However, exosomes from endothelial progenitor cells (EPCs) have not been tested in any stroke ... changes in the fractional anisotropy (FA), tensor weighted images (TWI), and tensor trace (TT). TWI is ...

The divergent fates and distinct disease states that cells acquire, can be traced to initial cell lineage differences that are formed ... and potentially promote neointima formation. One could trace ...

Researchers have developed a genetic "barcoding" method to trace how stem cells in embryos become neurons and inner ear cells ...

But how do stem and progenitor cells know when to differentiate and which cell lineage to produce and to send down the conveyor belt? The answer lies in a gene regulation method called epigenetic ...

Shihabeddin et al utilized single-cell RNA-Seq analysis of adult P23H zebrafish animals to identify transcription factors (e2fs, Prdm1a, Sp1) expressed selectively in neural progenitors and immature ...