When Grey's Anatomy took off as a cultural phenomenon in the mid-2000s, Patrick Dempsey's Dr. Derek Shepherd also swiftly became one of the biggest heartthrobs on television. Nicknamed "McDreamy ...

Grey's Anatomy introduced fans to the iconic Meredith Grey, but it also introduced them to the swoon-worthy Derek Shepherd. The pair were presented as the show's most desirable couple, making them ...