Could viral infections play a role in Huntington's disease? Research suggests Apolipoprotein B mRNA editing catalytic ...

People genetically susceptible to Huntington's disease often see their movement, mood, and cognition decline slowly over time.

APOBEC enzymes, which normally help fight viral infections by mutating viral DNA, cause repeat expansions and are unusually ...

People genetically susceptible to Huntington's disease often see their movement, mood, and cognition decline slowly over time ...

Researchers at Tufts University revealed a possible molecular mechanism explaining how the DNA repeats are broken and then expanded in the Huntington’s disease gene, pointing to a component of the ...

Approximately 23 years before a clinical diagnosis, CSF analysis showed very early signs of neurodegeneration with elevated ...

Researchers swap nitrogen and boron into DNA to create analogues that are geometrically and electrostatically equivalent to ...

IN the nucleic acids, cytosine is connected to a sugar residue through N 1 of the pyrimidine ring. Here we describe the results of an X-ray diffraction analysis of crystals of N 1-methyl cytosine.

Flucytosine ER + vocimagene amiretrorepvec is under clinical development by Denovo Biopharma and currently in Phase I for High-Grade Glioma. According to GlobalData, Phase I drugs for High-Grade ...