Kyler Murray threw for 242 yards and four touchdowns, two to Greg Dortch, and Arizona beat injury-depleted San Francisco.

The 49ers ended the season with just two takeaways in their last 10 games. They also gave up 40 or more points in their final ...

Arizona's offseason conversation will start with Murray. That's nothing new. It always starts with the quarterback.

San Francisco running back Isaac Guerendo exited the 49ers' season finale versus the Arizona Cardinals just four plays into ...

The San Francisco 49ers just lost 47-24 to the Arizona Cardinals. Here are the 49ers' grades for this performance.

The San Francisco 49ers concluded their 2024 season on the road against the Arizona Cardinals. Among the long list of of injured players not suiting up for the season finale was QB1 Brock Purdy, who ...

San Francisco 49ers running back Isaac Guerendo was carted off the field in the first quarter against the Arizona Cardinals.

GLENDALE -- San Francisco 49ers RB Isaac Guerendo was carted off the field in Week 18's matchup against the Arizona Cardinals. He has already been ruled out with a knee and ankle injury. On just the ...

San Francisco 49ers head coach Kyle Shanahan recapped the team's 47-24 loss to the Arizona Cardinals and evaluated the 49ers overall performance in Week 18.

Unfortunately, San Francisco 49ers' running back Isaac Guerendo was carted off the field early in the first quarter.

With Sunday’s win over the San Francisco 49ers, the Arizona Cardinals ’ position in the first round of the 2025 NFL Draft is set. They will pick 16th overall.

It’s finally over. The San Francisco 49ers lost to the Arizona Cardinals on Sunday to put a stamp on what was one of the ...