Fibrates was used as second-line therapy in a pregnant patient with PBC-associated pruritus who responded poorly to UDCA, a study found. In Obstetric Medicine, Harrington and colleagues presented one ...

Mycophenolate mofetil may have a role in alleviating liver injury secondary to drugs such as avacopan. An elderly female patient with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis ...

Researchers investigated the apparent close relationship between IGG4-RD and AAV and whether they arise from shared pathophysiological pathways. A 60-year-old woman was referred for fever and kidney ...

Nipocalimab plus standard of care resulted in better disease control throughout 24 weeks compared to placebo plus standard of care in patients with generalized myasthenia gravis. The US Food and Drug ...

Treatment-related adverse events were more frequent in the nipocalimab group than in the control group; however, they all were mild or moderate in severity. Nipocalimab, a monoclonal antibody with ...

The patient had a positive Darier’s sign, a key diagnostic clue in indolent systemic mastocytosis. An unusual case has been reported of a patient with indolent systemic mastocytosis (ISM), a form of ...

This study highlights the critical role of personalized medicine in optimizing outcomes for GD patients with significant cardiac risks. When administered according to pharmacogenomic guidelines, ...

Serum sickness is a rare but potentially severe complication of rituximab therapy. A patient with newly diagnosed progressive transformation of germinal centers (PTGC) associated with immunoglobulin ...

The patients receiving AHSCT had 5-year LFS of 46.3% and OS of 53.3%, which were better outcomes than those of the MRC UKALL XII/ECOG E2993 trial conducted from 2006 to 2010. Autologous hematopoietic ...

Cyclopamine significantly improved pulmonary hemodynamics and vascular remodeling in monocrotaline-induced PAH rat models. Cyclopamine treatment attenuated pulmonary vascular remodeling and improved ...

Scutellarein is a naturally occurring flavonoid compound derived from diverse sources. It shares antioxidant and anti-inflammatory properties with other well-known flavonoids. Scutellarein has been ...