Jay Manuel and Pamela Chavez gave fans a glimpse into their relationship while living with osteogenesis imperfecta type 3 ...

Jay & Pamela stars Jay Manuel and Pamela Chavez have tied the knot and In Touch can exclusively confirm when their nuptials ...

The big day has finally arrived for Jay and Pamela. Both have a rare genetic disorder called osteogenesis imperfecta type 3 ...

The TLC stars were born with the same rare genetic condition and have broken more than 400 bones between them.

This year, the group is fundraising for Shriners Children's in Greenville, South Carolina.

For the last 12 years, the Alee Shriners in Savannah have been hosting an 'Iron Butt Ride' fundraiser. It's a 24-hour ...

Her life embodies a paradox: fragility and fortitude intertwined. Each stitch in her embroidery carries the weight of her ...

Jay Manuel, 28, and Pamela Chavez, 30, were both born with a rare disorder called Osteogenesis Imperfecta Type III (OI).

From Washington to Wall Street, it's a crazy time for biotech. But as Ultragenyx Pharmaceutical Inc. celebrates its 15th ...

How a 1981 episode of 'Mister Rogers' Neighborhood' opened kids' eyes to one boy's story — and now inspires a new character ...

Jeff Erlanger was a longtime fan of Fred Rogers before appearing on his show, and the two became friends for life ...