Northwestern Medicine investigators have uncovered new insights into how metabolic dysfunction contributes to Parkinson's ...

Dr. Shuyang Zhang (Department of Rare Diseases, Peking Union Medical College Hospital) and Dr. He Huang (Shanghai Institute of Materia Medica, Chinese Academy of Sciences).

Such was the case for Hans Krebs, the biochemist who nabbed the award in 1953 for discovering the citric acid cycle, or “Krebs cycle”—the cellular pathway that converts carbohydrates, fats, and ...

and FADH 2 (reduced flavin adenine dinucleotide), that are produced by the oxidation of carbohydrates (the tricarboxylic acid (TCA) cycle) and fatty acids is coupled to the generation of an ...

Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect.

Glycolysis takes place in the cytoplasm. Within the mitochondrion, the citric acid cycle occurs in the mitochondrial matrix, and oxidative metabolism occurs at the internal folded mitochondrial ...