Northwestern Medicine investigators have uncovered new insights into how metabolic dysfunction contributes to Parkinson's ...

Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect.

Dr. Shuyang Zhang (Department of Rare Diseases, Peking Union Medical College Hospital) and Dr. He Huang (Shanghai Institute of Materia Medica, Chinese Academy of Sciences).

In addition, the team proposed that non-histone lactylation levels accumulate progressively from 1 week to 6 months (6 m), whereas histone lactylation levels decrease rapidly from 1 to 6 weeks ...

A subset of Parkinson’s disease is caused by CHCHD2, a gene which encodes a protein contained in the mitochondria of cells.

More information: Ling Cai et al, High Glucose Contribution to the TCA Cycle Is a Feature of Aggressive Non–Small Cell Lung Cancer in Patients, Cancer Discovery (2025). DOI: 10.1158/2159-8290.CD ...

Such was the case for Hans Krebs, the biochemist who nabbed the award in 1953 for discovering the citric acid cycle, or “Krebs cycle”—the cellular pathway that converts carbohydrates, fats, and ...

“It’s essentially a ‘hedge-your-bets’ approach,” said Ahmed. “It can create challenges for students on what to take, how many ...

Japan maintains impressive health standards with traditional practices like Washoku and Moritsuke. Manga artist Ami Shibata ...

PDHX acetylation promotes tumor progression by disrupting PDC assembly and activating lactylation-mediated gene expression.

Even well-studied bacteria diverge from E. coli in basic processes (e.g., the ins and outs of the TCA cycle), and there are also variations between and among countless laboratory and natural E.