This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

Researchers created replicas of 3D cell structures inside Minecraft and made them available for anyone to use in their own installation of the game.

Mitochondria play a crucial role in cellular energy production, and their dysfunction has long been linked to metabolic ...

Right now, approximately 20 billion red blood cells are busy traveling through your blood vessels. They are delivering oxygen ...

Northwestern Medicine scientists have discovered new details about how the human genome produces instructions for creating ...

Mitochondrial defects, however, are associated with the development of diseases such as type 2 diabetes. Patients who suffer from this disorder are unable to produce enough insulin or use the insulin ...

Mitochondrial damage is common in metabolic diseases like Diabetes, affecting insulin production and function in patients. Diabetics’ insulin-producing β-cells have abnormal mitochondria, impairing ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is a ...

With the strong associations established in epidemiologic studies and a dearth of evidence on the actual mechanisms by which ...

A group of scientists in China has revealed a novel mechanism whereby a short form of IL-18, generated by caspase-3 cleavage ...

When nucleus pulposus cells experience stress, the TRPV4 channel opens, allowing calcium influx (18). While controlled calcium influx is necessary for normal cellular function, excessive calcium entry ...

From the evidence of karyomeres in animal cells, the nucleus is regarded as a compound structure, and it was further suggested that the spindle is also compound, the real unit in mitosis being a ...