"We think the bacteria's ribosomes might be altering its structure just enough to prevent an antibiotic from binding effectively," says Anna Delgado-Tejedor, first author of the study and Ph.D ...

They focused on the bacteria's ribosomes, which are cellular micro-machines that are key to making proteins and translating ...

These differences are exploited by antibiotics, which are designed to inhibit the prokaryotic ribosomes of infectious bacteria without affecting eukaryotic ribosomes, thereby not interfering with ...

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal ...

none were previously known to target the bacterial ribosome—the protein-making machinery itself. Gerry Wright and his research team discovered lariocidin by examining soil samples from a ...

Lariocidin hits drug-resistant bacteria where others fail — by hijacking the ribosome at a new site, bypassing defences, and opening the door to a new generation of antibiotics. Lariocidin ...

What if we could fight climate change using bacteria that live on air? That's the vision behind a newly funded international research project led by ...

Williams and Research Scientist Anton Petrov compared three-dimensional structures of ribosomes from a variety of species of varying biological complexity, including humans, yeast, bacteria and ...

"Because this microbe can kill bacteria in a way that it can't evolve to evade, due to its protein production system called the ribosome, it has the potential to be a durable and lasting choice ...