Ribosomes are the sites in a cell in which protein synthesis takes place. Cells have many ribosomes, and the exact number depends on how active a particular cell is in synthesizing proteins.

The team also tested female knockout mice “and found that they were apparent normal with normal fertility and similar litter size,” Guo writes. Further experiments on mouse cell lines showed that ...

This commentary focuses on one potential mechanism by which ribosome biogenesis antagonizes cell-cycle progression until the cell has grown to an adequate size. Amaldi, F. & Pierandrei-Amaldi ...

View Full Profile. Learn about our Editorial Policies. Further investigation into SNORA13 revealed that it modifies RNA bases in the ribosome’s active site, suggesting that this small RNA may affect ...

HHMI scientists and their colleagues discover a new mechanism of protein synthesis. Ribosomes are the cell’s molecular machines, responsible for translating genetic information in messenger RNA into ...

We find that these inhibitors slow elongating ribosomes, thereby inducing a queue of pre-initiation complexes that can become positioned over and initiate from an otherwise poorly recognized start ...