A research team has uncovered a previously unknown type of immune signaling molecule—a novel compound combining histidine and ...

A cross-sectional study of 400 older adults with metabolic syndrome reveals that individuals with depression have distinct ...

Tuberculosis (TB) killed approximately 1.25 million people globally in 2023, surpassing all other infectious diseases, ...

In 2023, tuberculosis (TB) killed about 1.25 million people worldwide, more than any other infectious disease on Earth — even though it is curable. Months- or even years-long regimens of potent ...

A genomic study of gut microbes during antibiotic use finds selective sweeps in a DNA gyrase gene that drive resistance.

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal ...

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal cellular functions. The ...

RNA-based therapeutics have rapidly emerged over the past decade, offering a new class of medicines that differ significantly from conventional drugs. These therapies can be programmed to target or ...

The paper addresses an important unresolved mechanism of antibiotic resistance caused by a RNA-modifying enzyme Cfr ... due to methylation of the rRNA residue A2503 on the large ribosomal subunit.

RNA is a unique bio-macromolecule that can both record genetic information and perform biological functions in a variety of molecular processes, including transcription, splicing, translation, and ...

After extracting total RNA from the samples and removing the ribosomal RNA using a Ribo-Zero Gold rRNA Removal Kit (Illumina), the RNA was fragmented using fragment reagent. First-strand cDNA was ...