RNA acts as a messenger inside cells, carrying instructions from DNA that are translated into proteins that are essential for ...

Activator protein binding is thought to cause DNA to loop out, bringing the activator protein into physical proximity with RNA polymerase and the other proteins in the complex that promote the ...

which is crucial for gene regulation.An artwork illustrates the various structures the RNA-binding protein (shown as the ...

A study has found that an ancient protein motif that binds to nucleic acids is functionally "ambidextrous." This means that ...

siRNAs loaded in an Argonaute protein then target complementary single-stranded RNA (ssRNA) to guide specific gene silencing. Fukunaga and Doudna now show that SGS3 is an RNA-binding protein that ...

“Two structurally identical plant proteins exhibit varied substrate ... in the Journal of the American Chemical Society. The ...

The labs of Ryan Flynn at Boston Children’s Hospital and Konstantinos Tzelepis at the Cambridge Stem Cell Institute have found a readily druggable target on the surface of acute myeloid leukemia (AML) ...

Ribonucleic acid (RNA) molecules may be best known for their job ferrying the genetic information encoded in DNA to a cell's ...

The researchers used nuclear magnetic resonance (NMR) spectroscopy combined with advanced computational methods ...

With collaborators at the Cambridge (UK) Stem Cell Institute, led by Konstantinos Tzelepis, PhD, and Maria Eleftheriou, PhD, they show that one RNA-binding protein on the cell surface, NPM1 ...

With collaborators at the Cambridge (UK) Stem Cell Institute, led by Konstantinos Tzelepis, Ph.D., and Maria Eleftheriou, Ph.D., they show that one RNA-binding protein on the cell surface ...