The genetic basis of quantitative traits such as body weight and obesity is complex, with several hundred quantitative trait loci (QTLs) known to affect these and related traits in humans and mice. It ...

soton.ac.uk Chromosome 14 harbours an imprinted locus at 14q32. Maternal uniparental disomy of chromosome 14, paternal deletions and loss of methylation at the intergenic differentially methylated ...

Researchers at the Francis Crick Institute have found that the small intestine grows in response to pregnancy in mice. This ...

Scientists want to make a real-life Frankenstein's lab to create 'spare' bodies for use in medical trials and as a source of ...

De-extinction startup Colossal Biosciences has gene-edited mice to have mammoth-like features, creating what the company calls the Colossal Woolly Mouse. The lab mice, which have been modified to ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

The team also used Evo 2 to create a minimal bacterial genome with just 580,000 DNA letters and a 330,000-letter-long yeast chromosome. And they added a Morse code message to a mouse’s genome. To be ...

Subsequently, scientists learned more and more about the genome of the mouse: from the order of genes on individual chromosomes to the sequencing of the mouse genome in 2002. We now know that the ...

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

With curly whiskers and wavy, light hair that grows three times longer than that of an ordinary lab mouse, the genetically modified rodent embodies several woolly mammoth-like traits, according to ...