EMBO Press7d
miR-708-5p is elevated in bipolar patients and can induce mood disorder-associated behavior in mice
R-708-5p is a stress-regulated microRNA and a potential biomarker for the differential diagnosis of human mood disorders.
Frontiers13d
Exploring the impact of MiR-92a-3p on FOLFOX chemoresistance biomarker genes in colon cancer cell lines
Introduction: One of the primary obstacles faced by individuals with advanced colorectal cancer (CRC) is the potential development of acquired chemoresistance as the disease advances. Studies have ...
gut.bmj12d
IDDF2023-ABS-0169 Multi-omics profiling of human liver donors identifies the risks towards post-transplant diabetes mellitus
Three robust clusters were found in PTDM patients by unsupervised clustering, among which the C3 cluster had the highest infection risk ... these findings reveal that VEGFA-VEGFR2 is regulated by both ...
Frontiers12d
Transcriptomic analysis of adaptive mechanisms in response to inland saline-alkaline water in the mud crab, Scylla paramamosain
Total RNA was extracted using the mirVana miRNA Isolation Kit (Ambion ... were mapped to the reference genome using hisat2 (Kim et al., 2015). Hierarchical cluster analysis of DEGs was performed to ...
eLife13d
A dual ribosomal system in the zebrafish soma and germline
Shah and colleagues take advantage of the presence of maternal and somatic ribosomes in zebrafish and confirm their differential expression during development. The authors convincingly show that ...
Phys.org13d
News on biosensor
A small team of materials scientists and chemical engineers at Qingdao University, in China, has developed a self-powered, three-component biosensor that can kill bacteria in water samples. The ...
eLife18d
Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in early mouse embryos
This study presents a valuable finding on how the interplay between transcription factors SOX2 and OCT4 establishes the pluripotency network in early mouse embryos. The evidence supporting the claims ...
gut.bmj13d
Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans
Objective Increased de novo fatty acid (FA) synthesis and cholesterol biosynthesis have been independently described in many tumour types, including hepatocellular carcinoma (HCC). Conclusion Our ...