The 2025 NFL schedule release blows out the doors on Wednesday evening. While we already know the Detroit Lions home and road opponents for the coming season, the sequence and schedule of games haven't been unveiled.

With the NFL schedule officially unveiled, here is Lions OnSI's first game-by-game prediction for the Lions' 2025 season. Week 1 - Sunday, Sept. 7 -- at Packers (4:25 p.m. ET) Prediction: 30-23 win (1-0). Week 2 - Sunday, Sept. 14 -- vs. Bears (1 p.m. ET) Week 3 - Monday, Sept. 22 -- at Ravens (8:15 p.m. ET)

Buckle up, Lions fans. Dan Campbell’s squad will embark upon a challenging road to a third straight NFC North division crown in 2025.

The Detroit Lions announced Wednesday their 2025 regular season schedule that features 12 nationally-televised games, including at least one on each broadcast network, five prime-time games and a Christmas Day matchup at the Minnesota Vikings.

We don't know the 2025 NFL schedule yet but but we do know each team's opponents. Here's how all 32 teams rank by strength of schedule.