If you look closely at the fundamental discoveries that have changed human health, physician–scientists have been at the ...

It then travels along neuronal axons and reaches the nucleus of neurons in the ... by ‟ballooning” degeneration of keratinocytes, resulting in intraepidermal vesicles containing multinucleated giant ...

Read the paper: Overlapping nuclear import and export paths unveiled by two-colour MINFLUX In organisms that have cells with a nucleus, DNA is stored in this compartment, which is surrounded by a ...

Cells go to great lengths to maintain the integrity of this vast store of information. They constantly untangle knots in the ...

It diffuses into the nucleus, where the genome resides, through large pores. There, enzymes break down the metabolites into epigenetic marks known as acetyl groups and place them on histones to ...

An international collaboration between four scientists from Mainz, Valencia, Madrid, and Zurich has published new research in ...

Scientists apply principles of math and physics to unravel the mystery of how the endoplasmic reticulum, an organelle vital ...

Advancing single-cell research requires precise and reproducible tissue dissociation techniques. Manual methods can introduce variability, compromise cell viability and hinder downstream applications.

Machine-learning models then detect subtle changes in the images, such as changes to the size of the nucleus. Cell Painting is combined with optical pooled screening in PERISCOPE, which “barcodes” ...