Growth and maturation of cartilage of articular joints are dynamic processes mediated by cell fates and extracellular matrix metabolism. These processes are regulated by complex biochemical and ...

This research builds on previous work from the Stupp laboratory, which involved using “dancing molecules” to stimulate human cartilage cells to increase the production of tissue matrix proteins.

Our group has explored the regeneration of soft biological tissues through cell-extracellular matrix interactions ... Dissociated and reconstituted cartilage microparticles in densified collagen ...

It also presents a novel therapeutic approach for accelerating the healing of defective cartilage and promoting the regeneration of hyaline cartilage ... and slow matrix turnover of articular ...