We first address the etiopathophysiology of OA and the mechanisms responsible for breakdown of the cartilage extracellular matrix. We then discuss the potential of MSCs for articular cartilage ...

Medical Engineering & Engineering Medicine Innovation Center, Hangzhou International Innovation Institute, Beihang University, Hangzhou 311115, China Key Laboratory of Biomechanics and Mechanobiology ...

Invitrogen Cat# MA137493 Detects cartilage matrix in immunofluorescence (1:200) Antibody Anti-Collagen I (Rabbit monoclonal) Abcam Cat# ab138492 Used for extracellular matrix immunostaining (1:200) ...

(28−30) The primary objective of this study is to investigate the efficacy of a novel dual-network hydrogel system composed of LT-GelMA and F127DA in promoting the regeneration of ear cartilage ...

Hyaline cartilage, elastic cartilage ... In summary, the factors influencing cartilage regeneration include the extracellular matrix, mechanical loading, and genetic regulation, all of which ...

Growth and maturation of cartilage of articular joints are dynamic processes mediated by cell fates and extracellular matrix metabolism. These processes are regulated by complex biochemical and ...

Step 4: p-cMGP is secreted into the extracellular matrix or the circulation to inhibit soft tissue calcification, VSMC (vascular smooth muscle cell) trans-differentiation into OPC (osteochondrogenic ...

A wide range of transcription factors regulated by soluble extracellular ... matrix production that has a higher ratio of collagen type I to II than native tissue, and secondly, there is no evidence ...