A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication. Cell lines ...

Deoxyribonucleic acid (DNA) replication is fundamental to life, yet the precise mechanics of how helicases unwind the genome for replication remain unclear. A recent study published in Nature used ...

Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA conformations—referred ...

Ingrida Domarkienė, a geneticist at Vilnius University in Lithuania, discusses the exciting developments made possible by ...

In their new study, the researchers studied the DNA replication patterns in early embryos. "We discovered differences in the replication mechanisms of maternal and paternal DNA during the initial ...

Researchers from the University of Birmingham have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question.

A new study from Weill Cornell Medicine provides insights into how cells maintain the tiny end caps of chromosomes as they divide, a key process in keeping cells healthy.

A major new study has revealed that the genes we inherit at birth play a much larger role in cancer than previously ...

An INRS research team has identified a new family of enzymes that can make precise cuts in single-stranded DNA. A few years ago, the introduction of CRISPR technology marked a significant breakthrough ...

Researchers have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question.