A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication. Cell lines ...

Deoxyribonucleic acid (DNA) replication is fundamental to life, yet the precise mechanics of how helicases unwind the genome for replication remain unclear. A recent study published in Nature used ...

Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA conformations—referred ...

Ingrida Domarkienė, a geneticist at Vilnius University in Lithuania, discusses the exciting developments made possible by ...

Knowing how human DNA changes over generations is essential to estimating genetic disease risks and understanding how we ...

In their new study, the researchers studied the DNA replication patterns in early embryos. "We discovered differences in the replication mechanisms of maternal and paternal DNA during the initial ...

Researchers from the University of Birmingham have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question.

A major new study has revealed that the genes we inherit at birth play a much larger role in cancer than previously ...

Scientists have found a way to sample DNA out of the air on a nationwide scale, making it possible to someday track the health and well-being of species around the globe.

Researchers have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question.