Using its proprietary FBDD platform, Blacksmith discovered FG-2101, the prodrug form of FG-960, the first known non-hydroxamate LpxC inhibitor that exerted activity against LpxC at the nanomolar range ...

A SYSTEMATIC review and meta-analysis suggest that a 7-day course of antibiotics is as effective as a 14-day regimen for most patients with Gram-negative bloodstream infections. Researchers conducted ...

The Azure of Lagoon Rod is located in the new Azure Lagoon area of the Second Sea in Fisch. Make your way to this location, locate the ladder on the right, and buy the rod for 100,000 E$. The Azure of ...

The Verdant Shear Rod can be purchased at Lushgrove Island in the second sea for 100,000E$. Walk past the Shipwright, then the Angler, to reach the Merchant, where you will find the rod. Finally, this ...

Purpose. The appropriateness of combination therapy for infections caused by gram-negative organisms is examined. Summary. Mortality from Pseudomonas aeruginosa infection is particularly high ...

Nature Research Intelligence Topics enable transformational understanding and discovery in research by categorising any document into meaningful, accessible topics. Read this blog to understand ...

This study aimed to investigate the activity of colistin in combination with the anti-rheumatic drug auranofin against Col-R Gram-negative bacteria. The results of checkerboard analysis demonstrated ...

The prediction of antimicrobial resistance in Gram-negative bacteria, often the cause of serious systemic infections, is more challenging as genotype-to-phenotype (drug resistance) relationship is ...