While typically considered an intracellular antioxidant with tumor-promoting capabilities, glutathione (GSH ... dependent on the catabolic activity of γ-glutamyl-transferases (GGT) enzymes, which can ...

Researchers from the International Institute of Molecular and Cell Biology in Warsaw (IIMCB) have described a new mechanism ...

Our immune systems weaken as we get older, making fewer cells that fight infection and help us recover from illness and ...

A team of researchers has uncovered a previously unrecognized role of mitochondrial protein synthesis in the maintenance of intracellular iron distribution. Disruption of this process was found to ...

"ELOVL2 is a key enzyme necessary for synthesis of the omega−3 fatty acid DHA, one of the main components of all cell membranes," said co-corresponding author Dorota Skowronska-Krawczyk, an associate ...

transcending the limitations of traditional chemical synthesis. Acting as micro-factories, enzymes enable the efficient production of antibiotics, biofuels, high-value compounds, and other desired ...

Resolution of subjective symptoms was achieved in 63% of cases; AST diminished on average by 36%, ALT by 34% and GGT by 46%. Furthermore, the investigators reported a reduction in hepatomegaly ...

However, a significant difference was found in levels alanine aminotransferase (ALT), and alanine aminotransferase (AST), alkaline phosphatase (ALP), gamma glutamyl transferase (GGT), total bilirubin ...

Concordant with this amino acid deprivation, the integrated stress response (ISR) was activated with protein synthesis attenuation ... uridine monophosphate, GSSG: glutathione disulfide, F6P: fructose ...