The sCD13 protein has been previously identified by a rheumatology research team at the University of Michigan as a powerful inducer of inflammation in multiple autoimmune disorders, such as ...

Preclinical data shows IL1 family signals mediate systemic immune suppression.Blocking IL1RAP can overcome resistance to immune therapy ...

Notably, in a patient sub-group defined by biomarkers (eosinophils ≥300 cells/ml and elevated neutrophils), amlitelimab showed nominally significant and clinically meaningful improvements in ...

In recent years our traditional understanding of both macrophages and neutrophils has been greatly challenged. Previously thought to promote inflammatory ...

With an FDA review underway, Johnson & Johnson is aiming to “fundamentally change” how bladder cancer is treated. | With an ...

The prevalence of obesity in American adults is 40.3%. Obesity can be diet-induced over time when a person consumes more calories than they use, exacerbated by a diet high in fat and/or sugar. In ...

Danyelza is now a recommended treatment in NCCN guidelines for relapsed or refractory high-risk neuroblastoma, a type of ...

Notably, in a patient sub-group defined by biomarkers (eosinophils ≥300 cells/ml and elevated neutrophils), amlitelimab showed nominally significant and clinically meaningful improvements in ...

Knee trauma can lead to severe complications like chronic osteomyelitis, as shown in this rare paediatric case, which ...