Using cutting edge cryo-electron microscopy, the team of scientists were able to visualise a helicase enzyme (nature's DNA unzipping machine) in the process of unwinding DNA. DNA helicases are ...

Microbes - alive and thriving -- have been found sealed within a fracture of 2-billion-year-old rock beneath Earth's surface.

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

The double ring, spool-like structure of RAD52 protects replicating DNA in dividing cells. A study led by the University of ...

For the first time, researchers have filmed in real time the disassembly of DNA at the atomic scale. This strand separation is the first step in DNA replication. This breakthrough, published ...

Plants know how to defend themselves against pathogenic microorganisms. In turn, pathogens have sensors to detect such ...

Researchers at Pitt have produced the most detailed image to date of a bacteriophage–phage for short–that has allowed them to ...

A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic defects disrupt cellular energy production. Researchers have identified a molecule that helps ...

The POLG gene regulates the production of DNA polymerase gamma, an enzyme that copies mitochondrial ... including by means of ...