Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...

Interferon-induced cytoplasmic condensates enriched with ADP-ribosylation ... To determine whether ADPr condensate formation relies on transcription, we treated cells with the inhibitor Actinomycin D.

The use of human cell, mouse, and fly models afforded capture of distinct ... which shows progressive re-distribution to the cytoplasm. The effect of polyQ expansion on the HTT interaction with TCERG1 ...