Copyright: © 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies. Overall, the ACCURE study ...

Vedolizumab as a first-line biologic in UC offers cost savings and clinical benefits, improving QALYs compared to TNF-α inhibitors. In CD, vedolizumab provides incremental benefits but incurs ...

Background The risk of developing advanced neoplasia (AN; colorectal cancer and/or high-grade dysplasia) in ulcerative colitis (UC) patients with a low-grade dysplasia (LGD) lesion is variable and ...

A sudden attack of massive bleeding might also indicate fulminant colitis, a particularly severe form of colitis that affects the entire colon. Symptoms of dehydration include extreme thirst ...

1 Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China 2 Zigong Hospital of Traditional Chinese Medicine, Zigong, China Background: Ulcerative colitis (UC) is a chronic ...

The Phase 2 randomized, placebo-controlled study evaluated twelve patients (nine in the PL8177 arm and three in the placebo arm) with active ulcerative colitis, (defined as having a Mayo Endoscopic ...