As they may only be isolable in small quantities, have interesting biological activity and chemical structures, natural product synthesis poses an interesting challenge in organic chemistry.

Historically, small molecule drugs have been precisely designed down to the atomic scale. Considering their relatively large complex structures, nanomedicines have lagged behind. Researchers argue ...

Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level. The ...

Scientists have discovered how chemokines and G protein-coupled receptors selectively bind each other to control how cells move.

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

This useful study reports a method to detect and analyze a novel post-translational modification, lysine acetoacetylation (Kacac), finding it regulates protein metabolism pathways. The study unveils ...

Center for BioAnalytical Chemistry, Hefei National Laboratory of Physical Science at Microscale, University of Science and Technology of China, Hefei 230026, China Center for BioAnalytical Chemistry, ...

State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Center for New Organic Matter, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Research Center for Analytical ...

Nano-heterostructures and hetero-junctions, in particular, are gaining tremendous traction in chemical sensing. Because of unusual surface properties, materials with nano-scale features are ...

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