The cell must also pass through a series of checkpoints that ensure conditions are favorable for division. In order to move from one phase of its life cycle to the next, a cell must pass through ...

And, if key checkpoints are missed or repair genes ... Mutations in genes can cause cancer by accelerating cell division rates or inhibiting normal controls on the system, such as cell cycle ...

IDO1 and PDL1 are immune checkpoints with key roles in immune system regulation. Their relevance stems from their ability to suppress T-cell function. T-cells are vital to the body’s immune response ...

Cell division allows a single fertilized egg to develop into a living being, our skin to renew itself, and wounds to heal. Before each cell division, termed mitosis, the genetic information must first ...

resulting in cell division. WNK1 was important for progression around the cycle and for bypassing checkpoints which can slow down the process, as T cells without WNK1 progressed more slowly ...

The Institute of Cancer Research, London, is seeking partners to continue the development of a cancer biomarker for predicting susceptibility to drugs targeting cell ...

All cells are produced from other cells by the process of cell division. Cell division occurs when one cell divides to produce two new cells. Unicellular organisms use cell division to reproduce.