This observation led us to propose that a cell-cycle checkpoint, which we call for convenience the fusion checkpoint (FCP), prevents proliferation following accidental fusion, thus making fusion ...

Merck’s Phase III KEYNOTE-B96 trial shows significant overall and progression-free survival gains with Keytruda plus ...

Anticipates initiating the Company's Phase 3 accelerated approval trial of IFx-Hu2.0 as adjunctive therapy with Keytruda® (pembrolizumab) as a first-line therapy for ...

GEN2 is well tolerated with minimal toxicity and signs of pharmacodynamic activity in an ongoing Phase 1 dose escalation and ...

Indigenous Nigerian food plants show promise in fighting cancer by targeting cell death and inflammation, offering support ...

Cell cycle control depends on phosphorylation of many proteins by the kinase Cdk1. Here, the authors show that phosphorylation of Cdk1 substrates is influenced by a phosphate-binding pocket on the ...

A garda has been killed in the line of duty while carrying out a speeding checkpoint in north county Dublin. Gardaí said a motorcyclist struck Garda Kevin Flatley at the checkpoint on the R132 ...

A successful CRISPR knockin isn’t just about inserting DNA. It’s about ensuring that edit stays functional and reliable over ...

First patient dosed in DENALI Part 2a clinical trial of azenosertib in patients with Cyclin E1+ PROC. Topline data from DENALI Part 2 anticipated by year end 2026 with the potenti ...

May 7, 2025 — Scientists have uncovered a promising new way to enhance the effectiveness of vaccines by tapping into the potential of a specific type of immune cell, opening the door to long ...