Jared Goff and the Detroit Lions visit Levi’s Stadium for the final home game of this injury-riddled 49ers season Click to share on Facebook (Opens in new window) Click to share on Twitter ...

Either way, we’ll likely hear their names often on Monday Night Football, as one of those newcomers will be protecting 49ers’ quarterback Brock Purdy’s blindside against the Lions.

The 49ers are riding a tow game losing streak into Week 17. They are poised to increase it to three in their matchup with the Lions. Here are three reasons why the 49ers will lose to the Lions.

Another San Francisco 49ers starting offensive lineman is missing from practice. Starting right tackle Colton McKivitz did not participate in Friday's session. McKivitz was a limited participant ...

The Detroit Lions and San Francisco 49ers have released their final injury reports of the week ahead of their Monday night showdown in Week 17 and there are a total of six players ruled out and ...

The San Francisco 49ers are prepping for Week 17 against the Detroit Lions on Monday Night Football. What they're not prepping for is a playoff push in January. At 6-9, Kyle Shanahan and the 49ers ...

San Francisco 49ers offensive tackle Trent Williams is largely considered one of the greatest to ever play the position. With 11 Pro Bowls and four All-Pro teams under his belt, Williams has been ...

There doesn't seem to be any question about quarterback Brock Purdy's future with the San Francisco 49ers. All indicators are the team is happy with his development and that his contract extension ...

On Monday at 8:15 p.m. ET, two of the top offensive players in the NFL will be featured when Jahmyr Gibbs and the Detroit Lions visit George Kittle and the San Francisco 49ers. The Lions sport the ...

Heading into a matchup against the Detroit Lions (13-2), the San Francisco 49ers (6-9) are monitoring 15 players on their injury report. The Lions' (13-2) injury report currently has five players ...