Hollywood and NFL power couples captivate public imagination with high-profile relationships. From Taylor Swift and Travis ...

The Detroit Lions scored on five consecutive drives in the second half to pull away for a 40-34 win over the host San Francisco 49ers on the final "Monday Night Football" matchup of the season.

Jared Goff and the Detroit Lions visit Levi’s Stadium for the final home game of this injury-riddled 49ers season Click to share on Facebook (Opens in new window) Click to share on Twitter ...

SANTA CLARA -- The 49ers just lost 40-34 to the Detroit Lions. Here are the 49ers' grades for this emabarrassing performance. Brock Purdy was an extreme version of the quarterback he has been all ...

Either way, we’ll likely hear their names often on Monday Night Football, as one of those newcomers will be protecting 49ers’ quarterback Brock Purdy’s blindside against the Lions.

This offseason, expect the 49ers to sign at least one quarterback, maybe even two. That's because Brandon Allen and Joshua Dobbs both will be free agents. And neither one needs to return.

Brock Purdy threw for a career-high 377 yards and three touchdowns as the San Francisco 49ers fell to the Detroit Lions 40-34 at Levi's Stadium on Monday Night Football. Purdy also threw two ...

The Detroit Lions probably didn’t have to play their starters on Monday night, but did, and the blueprint for the rest of their season became clearer. The Lions can score a lot of points.

The Detroit Lions will square off with the San Francisco 49ers on Monday Night Football in Week 17 of the NFL season at Levi’s Stadium, scheduled to start at 8:15 p.m. EST. All week, questions ...

The San Francisco 49ers and Arizona Cardinals play on Sunday, Jan. 5 at the Cardinals' State Farm Stadium in a game on the NFL Week 18 schedule. Which team will win the NFL Week 18 game?