Jared Goff and the Detroit Lions visit Levi’s Stadium for the final home game of this injury-riddled 49ers season Click to share on Facebook (Opens in new window) Click to share on Twitter ...

The Detroit Lions probably didn’t have to play their starters on Monday night, but did, and the blueprint for the rest of their season became clearer. The Lions can score a lot of points.

The 49ers will be down another key starter against the Lions on Monday night. All-Pro cornerback Charvarius Ward will not be active when the 49ers take on the Lions. He is out with a "personal ...

The Detroit Lions scored on five consecutive drives in the second half to pull away for a 40-34 win over the host San Francisco 49ers on the final "Monday Night Football" matchup of the season.

For the San Francisco 49ers, it was a season that started with high hopes. With the team officially out of the playoffs, fans ...

Either way, we’ll likely hear their names often on Monday Night Football, as one of those newcomers will be protecting 49ers’ quarterback Brock Purdy’s blindside against the Lions.

George Kittle had a thoughtful and wholesome idea when he gave his teammates' wives, Olivia Culpo and Kristin Juszczyk, ...

Brock Purdy threw for a career-high 377 yards and three touchdowns as the San Francisco 49ers fell to the Detroit Lions 40-34 at Levi's Stadium on Monday Night Football. Purdy also threw two ...

San Francisco 49ers running back Isaac Guerendo is expected to play Monday night against the Detroit Lions, according to ESPN's Adam Schefter. More news: Titans Reveal RB Tony Pollard's Playing ...

Points, points, and more points. That was the theme of tonight's game between the 49ers and Lions. They combined for 74 points. Neither defense was good for the majority of the game. It was all ...