helicases and ATP work together in a coordinated cycle to drive DNA unwinding," De Biasio said. When Watson and Crick ...

During DNA replication, the unwinding of strands leaves a single strand vulnerable. How does the cell protect these strands from damage? How would you identify the protein that serves as a ...

Arthur Kornberg compared DNA to a tape recording of instructions that can be copied over and over. How do cells make these near-perfect copies, and does the process ever vary? In reality, the ...

The team thought it might be a good candidate for finding histones because the bacterium changes size throughout its lifecycle and thus would need to carefully time DNA compression and unwinding. As a ...

A large multi-subunit protein complex, called replisome, coordinates DNA unwinding with DNA synthesis at the fork. Over 20 distinct proteins and protein complexes, comprising over 50 gene products, ...

a topoisomerase II inhibitor which stops the action of DNA unwinding enzyme topoisomerase II during DNA synthesis causing DNA breaks to occur during S phase resulting in apoptosis which can be ...