helicases and ATP work together in a coordinated cycle to drive DNA unwinding," De Biasio said. When Watson and Crick ...

Scientists previously believed that ATP (adenosine triphosphate), the energy currency of cells, directly powered the ...

Arthur Kornberg compared DNA to a tape recording of instructions that can be copied over and over. How do cells make these near-perfect copies, and does the process ever vary? In reality, the ...

During DNA replication, the unwinding of strands leaves a single strand vulnerable. How does the cell protect these strands from damage? How would you identify the protein that serves as a ...

The team thought it might be a good candidate for finding histones because the bacterium changes size throughout its lifecycle and thus would need to carefully time DNA compression and unwinding. As a ...

A large multi-subunit protein complex, called replisome, coordinates DNA unwinding with DNA synthesis at the fork. Over 20 distinct proteins and protein complexes, comprising over 50 gene products, ...

a topoisomerase II inhibitor which stops the action of DNA unwinding enzyme topoisomerase II during DNA synthesis causing DNA breaks to occur during S phase resulting in apoptosis which can be ...